(1916 - 1978)
Médico cirujano. Contribuyó al desarrollo de la cirugía experimental y del trasplante de órganos en Cuba. Se dedicó también a los estudios de Cibernética aplicada a la Medicina y gran parte de su esfuerzo lo consagró a la urgente tarea de reformar los hospitales universitarios y al propio Plan de estudios de la Facultad de Medicina.
Biomedical Sciences
1989 | Advanced laboratory techniquesin the control of Tuberculosis
Main author: José A. Valdivia
Summary: There have been developed some diagnostic and new techniques that have allowed the consolidation of the National Laboratory of Reference of Tuberculosis and other mycobacteria. In the field of immunology, there were carried out studies on mycobacterial antigens, for the immunodiagnosis and immunotaxonomy, there were implemented electrophoresis techniques in different variants, and it was carried out the antigenic mycobacterial characterization through two-dimensional electrophoresis and HPLC methods. It has been developed a new classification method of M. tuberculosis, and there are used phagotypical markers, which is very important in the epidemic studies. Calculation techniques applied to taxonomy have been incorporated and some others of quick diagnosis have been developed, such as ELISA and CIE that could be introduced in the outlying laboratories. This way, it has been perfected a national system for the diagnosis and classification of M. tuberculosis and other mycobacteria, from the base levels to the National Laboratory of Reference. It means an important contribution to the National Program of Control of this disease and has allowed knowing, nationally, the   percentage of primary and secondary   resistance to antibacillar drugs in the new cases of tuberculosis, as well as their provincial distribution, which is very useful in order to adopt new chemi-terapeutic schemes and strategies. All what have been previously exposed contributes to reduce even more the morbidity rate of tuberculosis in Cuba (5.5 per 100 000 inhabitants, in 1989), and that is why this country has one of the lowest rates worldwide.PERFORMERS:   Institute  of  Tropical Medicine     "Pedro Kourí"