(1898 - 1977)
Abogado y escritor. Brillante intelectual marxista y luchador social. Aportó valiosas obras como poeta, latinoamericanista y martiano. El Consejo Mundial de la Paz le otorgó las Medallas de Plata y de Oro Joliot Curie, en 1959 y 1966, respectivamente.
Biomedical Sciences
1989 | Obtaining and   applying   epidermal growth factor
Main author: Julio Delgado Boada
Summary: It was carried out the transformation of the PIG39 plasmid that contains the gene that codifies the EGF, in yeast of Saccharomyces cerevisiae species. Since then, there were studied the following elements: stumps, cultivation means, production kinetics, protein location, among others. It was achieved a purification process in three steps, obtaining a product with more than 90% of purity, and it was determined its biological activity. It was obtained a formulation cream that contains EGF and silver sulfadiazine, which was very appropriate in preclinical and clinical studies, there were also obtained satisfactory results in the acceleration of epithelization in burnt persons. It has also been used in many kinds of cutaneous ulcers, as well as in radiogenic proctitis, in late ulcerous radiogenic lessions, in the prevention of radiodermitis and in the extravasations of cytostatics, with very good results in all the situations.PERFORMERS: Center of Genetic Engineering and Biotechnology, National Institute of Oncology and Radiology,