(1903 - 1964)
Físico y químico francés, gran amigo de Cuba. Su aporte principal a la ciencia estuvo relacionado con la agricultura y la ganadería, fue mundialmente conocido por su tesis sobre el pastoreo intensivo.
Biomedical Sciences
2002 | Development of a molecular diagnostic system for the qualitative detection of the RNA of Hepatitis C virus.
Main executives entity: Center for Immunoassay (1)
Main author: Del (1) Yaimé Josefina González González e Idania González Pérez.

The work consists on the development of an analytic procedure and the reagent play, for the detention of the RNA of Hepatitis C virus in sample of patient's serum or plasma, as well as its validation, using the nucleic acid amplification method through the polymerase chain reaction (PCR) and the hybridization in solid phase, adapted to Suma teams of national production.

The method was appropriately validated, with specificity, sensibility, detention limit, precision and hardiness necessary for its use in the infection's certain diagnosis. The country has this possibility, previously limited for the reagents' acquisition abroad, which are extremely expensive. The quality of the method was compared to one of international leaders in the market.

The use of this procedure will allow preselecting patients to be subjected to hepatic biopsy, with which the cost and the risks of this procedure decrease. With the procedures developed by the Immunoassay Center, it is possible the diagnosis and the assessment of the treatment for these patients, for prices from 1.5 to 3 times cheaper.

The work has the following references :< /p>

  • 1. Register Certification from the diagnosticians registration, emited by the Center for National Control of the Quality of Medicines (CECMED) in the current year,
  • 2. Reference from AIDS research laboratory on the quality of the method and the relative simplicity of its use. From the Gastroenterologist Institute and the Center for Medical-Surgical Research (CIMEQ) as users of the method in patient’s diagnosis and assessment, pointing out the social and economic impact of its extension in the country, which is recommended,
  • 3. An acceptance document of the publication of the method’s validation in Biologicals magazine. A document of reception of the articles about the use of this method in Tropical Medicine brazilian magazine. A document of reception of the articles about the performance of the method in Analytical Biochemistry magazine. Two documents of presentations of the method in scientific events.

We consider that it is the first registered molecular diagnostician developed in the country, result from a development work that implied elements of scientific and technical originality for the technology assimilation, also using national technological elements of national base with proper guarantees from the scientific and user’s points of view, with great potential impact.