It constitutes a contribution to the international science since it describes a new phagous able to induce toxigenicity to vibrio cholerae. It is proved the existence of a new VGJ? filamentous bacteriophage in Vibrio Cholerae virulent bacteria, which is able to transmit in an alternative way, ch olera toxine genesto the via normaly recognized by the CTX? Bacteriophage. This discovery could have an application in obtaining attenuating strains, with less reversion probability than the ones described before. This can pave the way to safer and less reactogenic vaccinal candidates or with less reversion possibilities to the virulence in the endemic areas.

It has a patent and a publication in Journal of Bacteriology , one of them recieved Nestle award which acknowledges the publication due to its novelty, originality and scientific value given to the world science.

This work has a great importance from the medical and social point of view, since there is no attenuated vaccine against cholera nowadays confering a long protection and being safe and low-reactogenic.