(1797 - 1879)
Sociólogo, historiador y economista. Se destacó por su postura opuesta a la esclavitud y contra la anexión de Cuba a los Estados Unidos.
Biomedical Sciences
2005 | Biophyand immunomodulating basis sustainign therapeutics with exogenous lung surfactantand SP-A protein in the Acute Respiratory Distress Syndrome
Main executives entity: National Center of Farming Sanity ( CENSA) (1)
Other entities: Center of Pharmaceutical Chemistry ( CQF ) (2), Institute of Pharmacy and Food (IFAL ) (3), Center for Natural Products ( CPN ) (4), Biochemistry and Molecular Biology Department of Complutens University of Madrid, Spain (5), Biochemistry Cathedra of Veterinarian Sciences Faculty of La Plata Nacional Argentina (6)
Main author: del CENSA: Odalis Blanco Hidalgo, Roberto Faure García, Janet Sánchez Calero, Elizabeth de Armas Sanabria
Coauthors: René Delgado Hernández(1), Jesús Pérez Gil(5), Octavio Fernández Limia (1)
Summary:

The results of this research, presented in a very understendable way, constitute the first of this type in our country, since they proved for the first time and at international level, the SURFACEN ( porcine origin cuban lung surfactant) biophysical, antiinflammatory and antimicrobial properties, as well as SP-A porcine protein antioxidant and antimicrobial activity.

Knowledge contributing tu understanding of SP-A action mechanism is given. Likewise it is proved for the first time that SURFACEN pharmaceutical product has also interphase properties similar to the ones present in natural surfactant and greater than an homologous foreign surfactant.

The used methods thoroughly applied by the authors have a high scientific level at worldwide level.

The new biphysical and immunomodulating properties stidied serves as pharmacological foundation for a further pharmaceutical formulation out of this surfactant and the protein in thje treatment of Acute Respiratory Distress Syndrome. Additionally, it contributes to surfactant field in seeking and sustaining a pharmaceutical formulation which can constitute a selecting therapy to a complex problem which have been not solved yet.

It has 11 supports, 4 of them from prestigious international institutions.

The results are gathered in 9 publications (2000-2005), 2 of them in journals with great impact and 7 are refferenced, as well as 17 presentations in National and International Congresses.